Stability liabilities of biotherapeutic proteins: Early assessment as mitigation strategy
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چکیده
منابع مشابه
Assessment of hepatotoxic liabilities by transcript profiling.
Male Wistar rats were treated with various model compounds or the appropriate vehicle controls in order to create a reference database for toxicogenomics assessment of novel compounds. Hepatotoxic compounds in the database were either known hepatotoxicants or showed hepatotoxicity during preclinical testing. Histopathology and clinical chemistry data were used to anchor the transcript profiles ...
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methods for detection, quantitation and characterization of antibody responses have been developed. The results can provide intelligence for patient safety and treatment as well as increased knowledge about the immune response to the drug. However, assays for antibodies in biological fluids are susceptible to a wide range of technical difficulties in addition to scientific challenges in their i...
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چکیده ندارد.
15 صفحه اولse Hydrocarbon liquefaction : viability as a peak oil mitigation strategy
1Global Energy Systems, Department of Earth Sciences, Uppsala University, Villavägen 16, 752 36 Uppsala, Sweden 2Moscow School of Economics, Moscow State University, Moscow, Russia 3Faculty of Economics, Higher School of Economics, Moscow, Russia 4The International College of Economics and Finance, Higher School of Economics, Moscow, Russia 5Post Peak Living, San Francisco, CA, USA 6Management ...
متن کاملHydrocarbon liquefaction: viability as a peak oil mitigation strategy.
Current world capacity of hydrocarbon liquefaction is around 400,000 barrels per day, providing a marginal share of the global liquid fuel supply. This study performs a broad review of technical, economic, environmental and supply chain issues related to coal-to-liquids (CTL) and gas-to-liquids (GTL). We find three issues predominate. First, significant amounts of coal and gas would be required...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical and Biomedical Analysis
سال: 2021
ISSN: 0731-7085
DOI: 10.1016/j.jpba.2020.113650